CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tsueda, K.
Right arrow Articles by Heine, M. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tsueda, K.
Right arrow Articles by Heine, M. F.

Canadian Journal of Anesthesia, Vol 38, 20-23, Copyright © 1991 by Canadian Anesthesiologists' Society

ARTICLES

Cardiac sympathetic tone in anaesthetized diabetics

K Tsueda, KC Huang, SW Dumont, TJ Wieman, MH Thomas and MF Heine
Department of Anesthesiology, University of Louisville, Kentucky 40292.

To assess cardiac sympathetic nervous function in diabetics, the heart rates attained following a pharmacological dose of intravenous atropine, 23 micrograms.kg-1, were studied under N2O, isoflurane anaesthesia in diabetics (n = 21) and nondiabetics (n = 30). Atropine-induced heart rate in diabetics was significantly lower than that in nondiabetics (95 +/- 14 (SD) bpm vs 109 +/- 12 bpm, P less than 0.001) and were closely related to preoperative orthostatic diastolic blood pressure change (r = 0.60, P less than 0.01). There was some correlation between the atropine-induced heart rate and preoperative RR-variation in diabetics (r = 0.50, P less than 0.05). The findings suggest that cardiac sympathetic function may also be impaired in diabetics with orthostatic hypotension.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1991 by the Canadian Anesthesiologists' Society.