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Canadian Journal of Anesthesia, Vol 14, 299-308, Copyright © 1967 by Canadian Anesthesiologists' Society

Oxygen Levels and Haemodynamics during Anaesthesia with Nitrous Oxide, Thiopental, and Curare

RICHARD A. THEYE M.D.1 and CHARLES J. RESTALL M.D.1

1 Mayo Clinic and Mayo Foundation: Section of Anaesthesiology, Rochester, Minnesota

Haemodynamic and blood gas studies have been carried out in ten patients during anaesthesia with N2O, thiopental, and curare and during operations for varicose veins. Similar observations have been made previously during anaesthesia with ether, halothane, or methoxyflurane in the same clinical situation. With N2O, thiopental, and curare, average values for cardiac output were somewhat lower than those observed during anaesthesia with ether but were somewhat higher than with halothane or methoxyflurane. Abnormally low values for cardiac output were noted in four of the ten patients, but these low values could not be ascribed to overdosage of thiopental. Values for right atrial O2 saturation were demonstrated to be useful indices of the interrelationships of cardiac output, arterial O2 content, and rate of metabolic consumption of O2.






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Copyright © 1967 by the Canadian Anesthesiologists' Society.