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Canadian Journal of Anesthesia, Vol 12, 179-191, Copyright © 1965 by Canadian Anesthesiologists' Society
1 Department of Anesthesiology, Hospital of Saint Raphael, New Haven, Connecticut
Two hundred, unselected, consecutive open-heart operations using cardiopulmonary bypass are reviewed with particular reference to methods and results. An attempt was made to correlate primary anaesthetic agents used and in-hospital mortality. Nitrous oxide was never implicated in any of the deaths where it was used as the primary anaesthetic agent. In those cases where halogenated agents were used, methoxyflurane had the highest in-hospital mortality rate, halothane was next, and fluroxene had the least number of deaths where anaesthesia could be implicated. On the basis of our results and interpretations, fluroxene would appear to be the anesthetic agent of choice in managing patients for open-heart surgery using cardiopulmonary bypass.
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