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Canadian Journal of Anesthesia, Vol 11, 633-639, Copyright © 1964 by Canadian Anesthesiologists' Society

The Role of the Anaesthetist in a Diagnostic Myasthenia Gravis Clinic

LEONARD C JENKINS BA, MD, CM, FRCP(C)1, J CHANG MD, FRCP(C)1, L ZELDOWICZ MD1, W J BUCKLER MD1, and H B GRAVES BA, MD, CM, FRCP(C)1

1 Departments of Anaesthesia, Neurology, and Physical Medicine, Vancouver General Hospital, and the University of British Columbia, Faculty of Medicine, Vancouver, BC

A modified method of electromyographic diagnosis for myasthema gravis using decamethomum is described The role of the anaesthetist in association with a neurologist and physiatrist in this myasthenia gravis diagnostic clinic is outlined

The combination of electromyographic techniques decamethomum and edrophomum has enabled the identification of three stages in the progression of myasthema gravis muscle (1) stage of resistance, (2) stage of dual block, (3) stage of myopathy (refractormess)

In contrast to the decamethomum test which enables the demonstration of a generalized change of neuromuscular transmission in the mild case of myasthema gravis (the group of cases which present a difficult problem of diagnosis), the "curare" test may fail. In the severe case the curare test may prove hazardous in addition whereas the neostigmme and edrophomum tests are often equivocal






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Copyright © 1964 by the Canadian Anesthesiologists' Society.