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Canadian Journal of Anesthesia, Vol 10, 217-227, Copyright © 1963 by Canadian Anesthesiologists' Society

Laboratory and Clinical Experience with Phenazocine during Anaesthesia

C. R. STEPHEN M.D.1 and ROBERT W. MACMILLAN M.D.1

1 Division of Anesthesia, Duke University Medical Center, Durham, North Carolina

Similar to other narcotic compounds, phenazocine is capable of inducing a reduction of the respiratory rate in animals and in man. This depression of respiration becomes more marked during a state of anaesthesia induced with thiamylal sodium.

The cardiovascular dynamics remain stable during phenazocine administration, although bradycardia develops, which is reversible by anticholinergie drugs. Phenazocine does not possess the histamine-releasing properties associated with meperidine.






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Copyright © 1963 by the Canadian Anesthesiologists' Society.